Cutting Edge Research: Interview with Dr. Daniel Reich on the Brain & Lymphatic System


Erika Lyons Richardson interviews Daniel Reich MD, PhD, a physician-scientist with the National Institutes of Health. MS & Me Interviews will air on Sunday, 11/12 at 3:00pm EST on the MS & Me Radio Network. Dr. Reich is a neurologist and neuroradiologist, Director of the Translational Neuroradiology Unit in NINDS (National Institute of Neurological Disorders & Stroke).

In his clinical practice Dr. Reich cares for patients with multiple sclerosis and other neurological diseases, and he also leads several clinical studies focusing on multiple sclerosis. Research in his lab focuses on the use of advanced MRI techniques to understand the sources of disability in multiple sclerosis and on ways of adapting those approaches for research trials and patient care. He is particularly interested in harnessing noninvasive imaging modalities to dissect biological mechanisms of tissue damage.

Dr. Reich will discuss his cutting edge research which led to the discovery of a lymphatic system in the brain. His team used advanced imaging techniques to identify drainage tubes. The team discovered lymphatic vessels in the dura, the leathery outer coating of the brain, that may serve to remove waste from the brain. These vessels are known to run alongside blood vessels, and provide a route for the recirculation of plasma and white blood cells through the body.

Dr. Reich’s findings indicate that lymphatic vessels may serve as a link between the brain and the immune system. This may have relevance to diseases including multiple sclerosis. This study was supported by the Intramural Research Programs at the NINDS and the National Cancer Institute, the National Multiple Sclerosis Society, and the Conrad N. Hilton Foundation.